The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

Outer membrane protein assembly factor BamC

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Outer membrane protein assembly factor BamC

Structural domains comprising this superfamily share the structure of the outer memebrane protein assembly factor BamC, a component of the essential five-protein beta-barrel assembly machinery (BAM) in E. coli. This BAM complex is responsible for recognition and assembly of outer membrane beta-barrel proteins, although BamC is not essential for its functionality. BamC, together with the other two non-essential protein assembly factors BamE and BamB, express a rather unspecific influence on the stability of the complex and the kinetic folding of selected OMP proteins.

BamC has evolved through the gene duplication of two conserved domains known to mediate protein interactions in structurally related complexes.

GO Diversity

Unique GO annotations
5 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
2137 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Domains: 3
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 3
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 1
Unique EC:
Unique GO: 5
Unique Species: 2137