The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

ATP synthase, E subunit, C-terminal

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: ATP synthase, E subunit, C-terminal

This superfamily includes the E subunit of ATP synthase as well as the archaebacterial ATP synthase E subunit.

Subunit E contains hendecad repeats (11/3) along the entirety of its N-terminal helix. The hendecad pattern is of the form a-b-c-d-e-f-g-h-i-j-k, with hydrophobic residues at positions a,d,e,h resulting in a right handed coiling of the helices PMID:23000382.

The C-terminal half of subunit E forms the majority of the head group and consists of a globular domain, which contains a four-stranded b-sheet and two a-helices followed by a C-terminal a-helical tail PMID:20173764.

PFAM:PF01991, INTERPRO:IPR002842,DOI:10.1016/j.str.2012.08.020,DOI:10.1038/ncomms1693,DOI:10.1038/nsmb.1761

GO Diversity

Unique GO annotations
55 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
3167 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Domains: 11
Domain clusters (>95% seq id): 3
Domain clusters (>35% seq id): 3
Unique PDBs: 7
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 5
Unique EC:
Unique GO: 55
Unique Species: 3167