The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

CKK domain

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: CKK domain

Structural domains comprising this superfamily share the structure of the C-terminal CKK domain of the calmodulin-regulated associated (or CAMSAP) family of proteins. CAMSAP proteins present an N-terminal region that includes a CH domain, a central region with a predicted coiled-coil, and this C-terminal CKK domain which is involved in binding CAMSAP proteins to microtubules PMID:19508979.

The structure of the CKK domain is a beta-barrel with an associated alpha-helical hairpin. Characteristically, the CKK domain has a single invariant tryptophan residue within the core of the predicted beta-barrel. Residues that interact with this Trp to form part of this core are highly conserved too.

GO Diversity

Unique GO annotations
42 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
496 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Domains: 2
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 2
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 11
Unique EC:
Unique GO: 42
Unique Species: 496