The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.
2.40.280.10
superfamily
Functional Families
Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
Superfamily: Small protein B
Small protein B (SmpB) binds to transfer messenger RNA (tmRNA) with high affinity to form the tmRNA-SmpB system. The function of this system is two-fold: one is to release stalled ribosomes from damaged messenger RNA that lacks an in-frame stop codon. The second is to target incompletely synthesised protein fragments for degradation, thereby acting as a quality control system.
This entry represents the SmpB protein, which is well conserved among prokaryotic species. A gene encoding an SmpB protein with similar mass and sequence has been identified in all prokaryotic genomes that have been sequenced. The appearance of SmpB in the organism with the smallest number of genes, Mycoplasma genitalium, provides additional evidence suggesting its importance. SmpB has an anti-parallel beta-barrel structure, with three helices packed outside the core of the barrel.
GO Diversity
Unique GO annotations
4 Unique GO terms
EC Diversity
Unique EC annotations
0 Unique EC terms
Species Diversity
Unique species annotations
14434 Unique species
Sequence/Structure Diversity
Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.
Superfamily Summary
A general summary of information for this superfamily.
| Structures | |
|---|---|
| Domains: | 10 |
| Domain clusters (>95% seq id): | 2 |
| Domain clusters (>35% seq id): | 1 |
| Unique PDBs: | 6 |
| Alignments | |
| Structural Clusters (5A): | 1 |
| Structural Clusters (9A): | 1 |
| FunFam Clusters: | 3 |
| Function | |
| Unique EC: | |
| Unique GO: | 4 |
| Taxonomy | |
| Unique Species: | 14434 |