The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Peptidase M41
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Peptidase M41

Structural domains comprising this superfamily share the structure of members of the peptidase M41 family, which belongs to a larger family of zinc metalloproteases. Members of this superfamily include the cell division protein FtsH and the yeast mitochondrial respiratory chain complexes assembly protein, a putative ATP-dependent protease required for assembly of the mitochondrial respiratory chain and ATPase complexes. FtsH is an integral membrane protein and seems to behave as an ATP-dependent zinc metallopeptidase that binds one zinc ion.

GO Diversity

Unique GO annotations
104 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
14431 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 41
Domain clusters (>95% seq id): 3
Domain clusters (>35% seq id): 1
Unique PDBs: 10
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 55
Function
Unique EC:
Unique GO: 104
Taxonomy
Unique Species: 14431