The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Cbb3-type cytochrome c oxidase, subunit P, N-terminal domain

Heme- and copper-containing terminal oxidases (HCOs) function as cytochrome c oxidases or as quinol oxidases in aerobic respiration but also play a role in oxygen scavenging and in maintaining redox homeostasis. HCOs are diverse in terms of subunit composition, electron donor, and heme type, resulting in different electron and proton transfer characteristics. Based on overall amino acid similarities of the central subunit and specific differences of the proton channels, the HCO superfamily is subdivided into three major families: A, B, and C. The prototypes of family C, comprising ~20% of HCOs, are the cbb3 oxidases. Family-C HCOs contain the central subunit (N) and either one (O) or two (O + P) additional subunits that are completely different from family A and B subunits. This entry represents the N-terminal domain of the P-subunit which is made up of 2 helices PMID:20576851.

GO Diversity

Unique GO annotations
13 Unique GO terms

EC Diversity

Unique EC annotations
6 Unique EC terms

Species Diversity

Unique species annotations
3355 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Domains: 8
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 2
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 0
Unique EC: 6
Unique GO: 13
Unique Species: 3355