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CATH Superfamily 1.20.120.1370

Regulator of RNA polymerase sigma(70) subunit, domain 4

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Regulator of RNA polymerase sigma(70) subunit, domain 4
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Regulator of RNA polymerase sigma(70) subunit, domain 4

This superfamily represents a structural domain of sigma 70 thatis a target for many transcriptional activators and has a key role in binding the RNAP beta-subunit flap-tip. Domain 4 comprises a compact structural core of three helices. The last two alpha-helices of the structural core make up the helix-turn-helix motif that is responsible for recognition of the promoter -35 element 13.

DOI:10.1016/j.jmb.2007.06.081

GO Diversity

Unique GO annotations
7 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
1438 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 2
Domain clusters (>95% seq id): 2
Domain clusters (>35% seq id): 1
Unique PDBs: 2
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 3
Function
Unique EC:
Unique GO: 7
Taxonomy
Unique Species: 1438