The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Inositol polyphosphate kinase

Inositol phosphates (InsPs) serve as a second messengers and thus regulate various signalling processes. Structural domains comprising this superfamily share the structure of inositol polyphosphate kinases (IPKs), the largest of the three major families of InsP kinases which catalyse sequential phosphorylations of InsPs. A very well characterized IPKs is inositol polyphosphate multikinase (IPMK) whose signaling functions in controlling mammalian target of rapamycin (mTOR) and adenosine monophosphate (AMP)-activated protein kinase (AMPK), two major central molecules in metabolism signaling networks.

GO Diversity

Unique GO annotations
89 Unique GO terms

EC Diversity

Unique EC annotations
12 Unique EC terms

Species Diversity

Unique species annotations
1343 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Domains: 23
Domain clusters (>95% seq id): 7
Domain clusters (>35% seq id): 4
Unique PDBs: 14
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 0
Unique EC: 12
Unique GO: 89
Unique Species: 1343