CATH Domain 6e5mA02

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.10	Thrombin, subunit H
	2.40.10.10	Trypsin-like serine proteases

Domain Context

CATH Clusters

Superfamily	Trypsin-like serine proteases
Functional Family	Cationic trypsin

Enzyme Information

3.4.21.4

Trypsin.

based on mapping to UniProt P00760

Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.

-!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.4.

UniProtKB Entries (2)

Q9S9E3	IBB_VIGUC Vigna unguiculata subsp. cylindrica Horsegram inhibitor 1
P00760	TRY1_BOVIN Bos taurus Cationic trypsin

PDB Structure

PDB	6E5M
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystallographic structure of a complex between trypsin and a nonapeptide derived from a Bowman-Birk inhibitor found in Vigna unguiculata seeds. Fernandes, J.P.C., Mehdad, A., Valadares, N.F., Mourao, C.B.F., Ventura, M.M., Barbosa, J.A.R.G., Freitas, S.M. Arch. Biochem. Biophys.