1 keywords

CATH Domain 5x0rB00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.565 Retinoid X Receptor
Homologous Superfamily 1.10.565.10 Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily Retinoid X Receptor
Functional Family Nuclear receptor subfamily 1 group I member 2

Enzyme Information

UniProtKB Entries (1)

Q15788
NCOA1_HUMAN
Homo sapiens
Nuclear receptor coactivator 1

PDB Structure

PDB 5X0R
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
SPA70 is a potent antagonist of human pregnane X receptor.
Lin, W., Wang, Y.M., Chai, S.C., Lv, L., Zheng, J., Wu, J., Zhang, Q., Wang, Y.D., Griffin, P.R., Chen, T.
Nat Commun