1 keywords

CATH Domain 5ufjB00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.490 Globin-like
Homologous Superfamily 1.10.490.10 Globins

Domain Context

CATH Clusters

Superfamily Globins
Functional Family Hemoglobin subunit beta

Enzyme Information

UniProtKB Entries (1)

P68871
HBB_HUMAN
Homo sapiens
Hemoglobin subunit beta

PDB Structure

PDB 5UFJ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Discovery of GBT440, an Orally Bioavailable R-State Stabilizer of Sickle Cell Hemoglobin.
Metcalf, B., Chuang, C., Dufu, K., Patel, M.P., Silva-Garcia, A., Johnson, C., Lu, Q., Partridge, J.R., Patskovska, L., Patskovsky, Y., Almo, S.C., Jacobson, M.P., Hua, L., Xu, Q., Gwaltney, S.L., Yee, C., Harris, J., Morgan, B.P., James, J., Xu, D., Hutchaleelaha, A., Paulvannan, K., Oksenberg, D., Li, Z.
ACS Med Chem Lett