CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.450.410
Functional Family

Enzyme Information

4.99.1.2
Alkylmercury lyase.
based on mapping to UniProt P77072
An alkylmercury + H(+) = an alkane + Hg(2+).
-!- Acts on CH(3)Hg(+) and a number of other alkylmercury compounds, in the presence of cysteine or other thiols, liberating mercury as a mercaptide.

UniProtKB Entries (1)

P77072
MERB_ECOLX
Escherichia coli
Alkylmercury lyase

PDB Structure

PDB 5U7A
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural and Biochemical Characterization of Organotin and Organolead Compounds Binding to the Organomercurial Lyase MerB Provide New Insights into Its Mechanism of Carbon-Metal Bond Cleavage.
Wahba, H.M., Stevenson, M.J., Mansour, A., Sygusch, J., Wilcox, D.E., Omichinski, J.G.
J. Am. Chem. Soc.