CATH Classification

Domain Context

CATH Clusters

Superfamily Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Functional Family

Enzyme Information

2.7.1.161
CTP-dependent riboflavin kinase.
based on mapping to UniProt Q9HJA6
CTP + riboflavin = CDP + FMN.
-!- This archaeal enzyme differs from EC 2.7.1.26 in using CTP as the donor nucleotide. -!- UTP, but not ATP or GTP, can also act as a phosphate donor but it is at least an order of magnitude less efficient than CTP. -!- Formerly EC 2.7.1.n2.

UniProtKB Entries (1)

Q9HJA6
RIFK_THEAC
Thermoplasma acidophilum DSM 1728
Riboflavin kinase

PDB Structure

PDB 5TRD
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of RbkR (Riboflavin Kinase) from Thermoplasma acidophilum determined in complex with CTP and its cognate DNA operator
Vetting, M.W., Rodionova, I.A., Li, X., Osterman, A.L., Rodionov, D.A., Almo, S.C.
To be published