CATH Classification

Domain Context

CATH Clusters

Superfamily 3.30.1360.150
Functional Family Alkaline phosphatase PafA

Enzyme Information

3.1.3.1
Alkaline phosphatase.
based on mapping to UniProt Q9KJX5
A phosphate monoester + H(2)O = an alcohol + phosphate.
-!- Active at a high pH optimum. -!- Wide specificity. -!- Also catalyzes transphosphorylations. -!- Some enzymes hydrolyze diphosphate (cf. EC 3.6.1.1).

UniProtKB Entries (1)

Q9KJX5
ALPH_ELIME
Elizabethkingia meningoseptica
Alkaline phosphatase PafA

PDB Structure

PDB 5TJ3
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Mechanistic and Evolutionary Insights from Comparative Enzymology of Phosphomonoesterases and Phosphodiesterases across the Alkaline Phosphatase Superfamily.
Sunden, F., AlSadhan, I., Lyubimov, A.Y., Ressl, S., Wiersma-Koch, H., Borland, J., Brown, C.L., Johnson, T.A., Singh, Z., Herschlag, D.
J.Am.Chem.Soc.