1 keywords

CATH Domain 5nfuA01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.1120 Arylsulfatase, C-terminal domain
Homologous Superfamily 3.30.1120.30 POLO box domain

Domain Context

CATH Clusters

Superfamily POLO box domain
Functional Family Serine/threonine-protein kinase PLK

Enzyme Information

UniProtKB Entries (0)

PDB Structure

PDB 5NFU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A cryptic hydrophobic pocket in the polo-box domain of the polo-like kinase PLK1 regulates substrate recognition and mitotic chromosome segregation.
Sharma, P., Mahen, R., Rossmann, M., Stokes, J.E., Hardwick, B., Huggins, D.J., Emery, A., Kunciw, D.L., Hyvonen, M., Spring, D.R., McKenzie, G.J., Venkitaraman, A.R.
Sci Rep