1 keywords

CATH Domain 5nfhA01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.620 HUPs

Domain Context

CATH Clusters

Superfamily HUPs
Functional Family methionine--tRNA ligase, mitochondrial

Enzyme Information

UniProtKB Entries (1)

Q38C91
Q38C91_TRYB2
Trypanosoma brucei brucei TREU927
Methionyl-tRNA synthetase, putative

PDB Structure

PDB 5NFH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Chemical Validation of Methionyl-tRNA Synthetase as a Druggable Target in Leishmania donovani.
Torrie, L.S., Brand, S., Robinson, D.A., Ko, E.J., Stojanovski, L., Simeons, F.R.C., Wyllie, S., Thomas, J., Ellis, L., Osuna-Cabello, M., Epemolu, O., Nuhs, A., Riley, J., MacLean, L., Manthri, S., Read, K.D., Gilbert, I.H., Fairlamb, A.H., De Rycker, M.
ACS Infect Dis