CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P9WI69
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P9WI69
PKNI_MYCTU
Mycobacterium tuberculosis H37Rv
Serine/threonine-protein kinase PknI

PDB Structure

PDB 5M08
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The crystal structure of PknI from Mycobacterium tuberculosis shows an inactive, pseudokinase-like conformation.
Lisa, M.N., Wagner, T., Alexandre, M., Barilone, N., Raynal, B., Alzari, P.M., Bellinzoni, M.
FEBS J.