CATH Classification

Domain Context

CATH Clusters

Superfamily ATP synthase, gamma subunit, helix hairpin domain
Functional Family Lysine-specific histone demethylase 1A

Enzyme Information

1.-.-.-
Oxidoreductases.
based on mapping to UniProt O60341

UniProtKB Entries (1)

O60341
KDM1A_HUMAN
Homo sapiens
Lysine-specific histone demethylase 1A

PDB Structure

PDB 5L3F
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Polymyxins and quinazolines are LSD1/KDM1A inhibitors with unusual structural features.
Speranzini, V., Rotili, D., Ciossani, G., Pilotto, S., Marrocco, B., Forgione, M., Lucidi, A., Forneris, F., Mehdipour, P., Velankar, S., Mai, A., Mattevi, A.
Sci Adv