CATH Classification

Domain Context

CATH Clusters

Superfamily DD-peptidase/beta-lactamase superfamily
Functional Family glutaminase kidney isoform, mitochondrial

Enzyme Information

3.5.1.2
Glutaminase.
based on mapping to UniProt O94925
L-glutamine + H(2)O = L-glutamate + NH(3).

UniProtKB Entries (1)

O94925
GLSK_HUMAN
Homo sapiens
Glutaminase kidney isoform, mitochondrial

PDB Structure

PDB 5JYP
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for exploring the allosteric inhibition of human kidney type glutaminase.
Ramachandran, S., Pan, C.Q., Zimmermann, S.C., Duvall, B., Tsukamoto, T., Low, B.C., Sivaraman, J.
Oncotarget