CATH Domain 5jvtD00

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.10	Arc Repressor Mutant, subunit A
	1.10.10.10	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain

Domain Context

CATH Clusters

Superfamily	Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
Functional Family	Ets at 65A, isoform C

Enzyme Information

UniProtKB Entries (1)

FLI1_HUMAN

Homo sapiens

Friend leukemia integration 1 transcription factor

PDB Structure

PDB	5JVT
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structures of mithramycin analogues bound to DNA and implications for targeting transcription factor FLI1. Hou, C., Weidenbach, S., Cano, K.E., Wang, Z., Mitra, P., Ivanov, D.N., Rohr, J., Tsodikov, O.V. Nucleic Acids Res.