CATH Classification

Domain Context

CATH Clusters

Superfamily 2.160.20.20
Functional Family

Enzyme Information

3.4.21.-
Serine endopeptidases.
based on mapping to UniProt Q8VSL2

UniProtKB Entries (1)

Q8VSL2
SEPA_SHIFL
Shigella flexneri
Serine protease SepA autotransporter

PDB Structure

PDB 5J44
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Shigella depends on SepA to destabilize the intestinal epithelial integrity via cofilin activation.
Maldonado-Contreras, A., Birtley, J.R., Boll, E., Zhao, Y., Mumy, K.L., Toscano, J., Ayehunie, S., Reinecker, H.C., Stern, L.J., McCormick, B.A.
Gut Microbes
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