CATH Domain 5j40A03

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family

Enzyme Information

3.6.4.-

Acting on ATP; involved in cellular and subcellular movement.

based on mapping to UniProt P03072

UniProtKB Entries (1)

LT_POVJC

JC polyomavirus

Large T antigen

PDB Structure

PDB	5J40
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Fragment-Based Discovery of Dual JC Virus and BK Virus Helicase Inhibitors. Bonafoux, D., Nanthakumar, S., Bandarage, U.K., Memmott, C., Lowe, D., Aronov, A.M., Bhisetti, G.R., Bonanno, K.C., Coll, J., Leeman, J., Lepre, C.A., Lu, F., Perola, E., Rijnbrand, R., Taylor, W.P., Wilson, D., Zhou, Y., Zwahlen, J., Ter Haar, E. J.Med.Chem.