CATH Classification

Domain Context

CATH Clusters

Superfamily Tetracycline Repressor, domain 2
Functional Family HTH-type transcriptional regulator EthR

Enzyme Information

UniProtKB Entries (1)

P9WMC1
ETHR_MYCTU
Mycobacterium tuberculosis H37Rv
HTH-type transcriptional regulator EthR

PDB Structure

PDB 5J3L
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Fragment-Sized EthR Inhibitors Exhibit Exceptionally Strong Ethionamide Boosting Effect in Whole-Cell Mycobacterium tuberculosis Assays.
Nikiforov, P.O., Blaszczyk, M., Surade, S., Boshoff, H.I., Sajid, A., Delorme, V., Deboosere, N., Brodin, P., Baulard, A.R., Barry, C.E., Blundell, T.L., Abell, C.
ACS Chem. Biol.