CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.472 | Cyclin A; domain 1 |
|
1.10.472.10 | Cyclin-like |
Domain Context
CATH Clusters
| Superfamily | Cyclin-like |
| Functional Family | Cyclin-A2 |
Enzyme Information
UniProtKB Entries (1)
| P24941 |
CDK2_HUMAN
Homo sapiens
Cyclin-dependent kinase 2
|
PDB Structure
| PDB | 5IF1 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Conformational Adaption May Explain the Slow Dissociation Kinetics of Roniciclib (BAY 1000394), a Type I CDK Inhibitor with Kinetic Selectivity for CDK2 and CDK9.
Acs Chem.Biol.
|