CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Non-specific serine/threonine protein kinase

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt O96013
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

O96013
PAK4_HUMAN
Homo sapiens
Serine/threonine-protein kinase PAK 4

PDB Structure

PDB 5I0B
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The discovery and the structural basis of an imidazo[4,5-b]pyridine-based p21-activated kinase 4 inhibitor
Park, J.K., Kim, S., Han, Y.J., Kim, S.H., Kang, N.S., Lee, H., Park, S.Y.
Bioorg. Med. Chem. Lett.