CATH Classification

Domain Context

CATH Clusters

Superfamily Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
Functional Family 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase

Enzyme Information

2.7.7.60
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase.
based on mapping to UniProt Q06755
CTP + 2-C-methyl-D-erythritol 4-phosphate = diphosphate + 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol.
-!- ATP or UTP can replace CTP, but both are less effective. -!- GTP and TTP are not substrates. -!- Forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis.

UniProtKB Entries (1)

Q06755
ISPD_BACSU
Bacillus subtilis subsp. subtilis str. 168
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase

PDB Structure

PDB 5HS2
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A structural and functional study on the 2-C-methyl-d-erythritol-4-phosphate cytidyltransferase (IspD) from Bacillus subtilis.
Jin, Y., Liu, Z., Li, Y., Liu, W., Tao, Y., Wang, G.
Sci Rep