CATH Classification

Domain Context

CATH Clusters

Superfamily DD-peptidase/beta-lactamase superfamily
Functional Family glutaminase kidney isoform, mitochondrial

Enzyme Information

3.5.1.2
Glutaminase.
based on mapping to UniProt O94925
L-glutamine + H(2)O = L-glutamate + NH(3).

UniProtKB Entries (1)

O94925
GLSK_HUMAN
Homo sapiens
Glutaminase kidney isoform, mitochondrial

PDB Structure

PDB 5HL1
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of the clinically relevant glutaminase inhibitot CB-839 in complex with glutaminase C
Huang, Q., Katt, W.P., McDermott, L.A., Cerione, R.A.
To Be Published