CATH Classification

Domain Context

CATH Clusters

Superfamily Ribonuclease Z/Hydroxyacylglutathione hydrolase-like
Functional Family Quinolone signal response protein

Enzyme Information

3.1.2.32
2-aminobenzoylacetyl-CoA thioesterase.
based on mapping to UniProt P20581
2-aminobenzoylacetyl-CoA + H(2)O = 2-aminobenzoylacetate + CoA.
-!- The enzyme, characterized from the bacterium Pseudomonas aeruginosa, participates in the production of the signal molecule 2-heptyl-4(1H)- quinolone (HHQ).

UniProtKB Entries (1)

P20581
PQSE_PSEAE
Pseudomonas aeruginosa PAO1
2-aminobenzoylacetyl-CoA thioesterase

PDB Structure

PDB 5HIO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Dissecting the Multiple Roles of PqsE in Pseudomonas aeruginosa Virulence by Discovery of Small Tool Compounds.
Zender, M., Witzgall, F., Drees, S.L., Weidel, E., Maurer, C.K., Fetzner, S., Blankenfeldt, W., Empting, M., Hartmann, R.W.
Acs Chem.Biol.