CATH Domain 5glfA02

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.10	Roll
	3.10.330	Vcp-like ATPase; Chain A, domain 2
	3.10.330.10

Domain Context

CATH Clusters

Superfamily	3.10.330.10
Functional Family	Cell division control 48

Enzyme Information

3.6.4.6

Vesicle-fusing ATPase.

based on mapping to UniProt P55072

ATP + H(2)O = ADP + phosphate.

-!- A large family of ATP-hydrolyzing enzymes involved in the heterotypic fusion of membrane vesicles with target membranes and the homotypic fusion of various membrane compartments. -!- They belong to the AAA-type (ATPase associated with a variety of cell activities) ATPase superfamily. -!- They include peroxin, which apparently is involved in Zellweger's syndrome.

UniProtKB Entries (1)

P55072

TERA_HUMAN

Homo sapiens

Transitional endoplasmic reticulum ATPase

PDB Structure

PDB	5GLF
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural insights into the interaction of human p97 N-terminal domain and SHP motif in Derlin-1 rhomboid pseudoprotease. Lim, J.J., Lee, Y., Yoon, S.Y., Ly, T.T., Kang, J.Y., Youn, H.S., An, J.Y., Lee, J.G., Park, K.R., Kim, T.G., Yang, J.K., Jun, Y., Eom, S.H. FEBS Lett.