CATH Classification

Domain Context

CATH Clusters

Superfamily 5' to 3' exonuclease, C-terminal subdomain
Functional Family U5 small nuclear ribonucleoprotein helicase

Enzyme Information

3.6.4.13
RNA helicase.
based on mapping to UniProt P32639
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).

UniProtKB Entries (1)

P40018
RSMB_YEAST
Saccharomyces cerevisiae S288C
Small nuclear ribonucleoprotein-associated protein B

PDB Structure

PDB 5GAN
External Links
Method ELECTRON MICROSCOPY
Organism
Primary Citation
Cryo-EM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 angstrom resolution.
Nguyen, T.H., Galej, W.P., Bai, X.C., Oubridge, C., Newman, A.J., Scheres, S.H., Nagai, K.
Nature