1 keywords

CATH Domain 5fv1L00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.40 Immunoglobulin-like
Homologous Superfamily 2.60.40.10 Immunoglobulins

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Immunoglobulin kappa chain variable 12-38

Enzyme Information

UniProtKB Entries (1)

P15692
VEGFA_HUMAN
Homo sapiens
Vascular endothelial growth factor A

PDB Structure

PDB 5FV1
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Novel Interaction Mechanism of a Domain Antibody Based Inhibitor of Human Vascular Endothelial Growth Factor with Greater Potency Than Ranibizumab and Bevacizumab and Improved Capacity Over Aflibercept.
Walker, A., Chung, C., Neu, M., Burman, M., Batuwangala, T., Jones, G., Tang, C., Steward, M., Mullin, M., Tournier, N., Lewis, A., Korczynska, J., Chung, V., Catchpole, I.
J.Biol.Chem.