CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.1350.10
Functional Family Holliday junction resolvase RecU

Enzyme Information

3.1.22.4
Crossover junction endodeoxyribonuclease.
based on mapping to UniProt P39792
Endonucleolytic cleavage at a junction such as a reciprocal single- stranded crossover between two homologous DNA duplexes (Holliday junction).
-!- The enzyme from Saccharomyces cerevisiae has no endonuclease or exonuclease activity on single-stranded or double-stranded DNA molecules that do not contain Holliday junctions.

UniProtKB Entries (1)

P39792
RECU_BACSU
Bacillus subtilis subsp. subtilis str. 168
Holliday junction resolvase RecU

PDB Structure

PDB 5FDK
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural insights into dynamics of RecU-HJ complex formation elucidates key role of NTR and stalk region toward formation of reactive state.
Khavnekar, S., Dantu, S.C., Sedelnikova, S., Ayora, S., Rafferty, J., Kale, A.
Nucleic Acids Res.