CATH Classification

Domain Context

CATH Clusters

Superfamily NAD(P)-binding Rossmann-like Domain
Functional Family 17-beta-hydroxysteroid dehydrogenase 14

Enzyme Information

1.1.1.-
With NAD(+) or NADP(+) as acceptor.
based on mapping to UniProt Q9BPX1

UniProtKB Entries (1)

Q9BPX1
DHB14_HUMAN
Homo sapiens
17-beta-hydroxysteroid dehydrogenase 14

PDB Structure

PDB 5EN4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
First Structure-Activity Relationship of 17 beta-Hydroxysteroid Dehydrogenase Type 14 Nonsteroidal Inhibitors and Crystal Structures in Complex with the Enzyme.
Braun, F., Bertoletti, N., Moller, G., Adamski, J., Steinmetzer, T., Salah, M., Abdelsamie, A.S., van Koppen, C.J., Heine, A., Klebe, G., Marchais-Oberwinkler, S.
J. Med. Chem.