CATH Classification

Domain Context

CATH Clusters

Superfamily Glutaredoxin
Functional Family Tau class glutathione S-transferase

Enzyme Information

2.5.1.18
Glutathione transferase.
based on mapping to UniProt Q8L7C9
RX + glutathione = HX + R-S-glutathione.
-!- A group of enzymes of broad specificity. -!- R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. -!- Also catalyzes the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange. -!- Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and EC 4.4.1.7.

UniProtKB Entries (1)

Q8L7C9
GSTUK_ARATH
Arabidopsis thaliana
Glutathione S-transferase U20

PDB Structure

PDB 5ECQ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis of jasmonate-amido synthetase FIN219 in complex with glutathione S-transferase FIP1 during the JA signal regulation
Chen, C.Y., Ho, S.S., Kuo, T.Y., Hsieh, H.L., Cheng, Y.S.
Proc. Natl. Acad. Sci. U.S.A.