CATH Classification

Domain Context

CATH Clusters

Superfamily Alkaline Phosphatase, subunit A
Functional Family Ectonucleotide pyrophosphatase/phosphodiesterase family member 2

Enzyme Information

3.1.4.39
Alkylglycerophosphoethanolamine phosphodiesterase.
based on mapping to UniProt Q64610
1-alkyl-sn-glycero-3-phosphoethanolamine + H(2)O = 1-alkyl-sn-glycerol 3-phosphate + ethanolamine.
-!- Also acts on acyl and choline analogs.

UniProtKB Entries (1)

Q64610
ENPP2_RAT
Rattus norvegicus
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2

PDB Structure

PDB 5DLV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Steroid binding to Autotaxin links bile salts and lysophosphatidic acid signalling.
Keune, W.J., Hausmann, J., Bolier, R., Tolenaars, D., Kremer, A., Heidebrecht, T., Joosten, R.P., Sunkara, M., Morris, A.J., Matas-Rico, E., Moolenaar, W.H., Oude Elferink, R.P., Perrakis, A.
Nat Commun