CATH Classification

Domain Context

CATH Clusters

Superfamily Bromodomain-like
Functional Family Bromodomain-containing protein 4

Enzyme Information

UniProtKB Entries (1)

O60885
BRD4_HUMAN
Homo sapiens
Bromodomain-containing protein 4

PDB Structure

PDB 5CS8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Discovery of Benzo[cd]indol-2(1H)-ones as Potent and Specific BET Bromodomain Inhibitors: Structure-Based Virtual Screening, Optimization, and Biological Evaluation
Xue, X., Zhang, Y., Liu, Z., Song, M., Xing, Y., Xiang, Q., Wang, Z., Tu, Z., Zhou, Y., Ding, K., Xu, Y.
J.Med.Chem.