CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.1190.20
Functional Family

Enzyme Information

2.7.1.50
Hydroxyethylthiazole kinase.
based on mapping to UniProt Q6GEY3
ATP + 4-methyl-5-(2-hydroxyethyl)thiazole = ADP + 4-methyl-5- (2-phosphonooxyethyl)thiazole.

UniProtKB Entries (1)

Q6GEY3
THIM_STAAR
Staphylococcus aureus subsp. aureus MRSA252
Hydroxyethylthiazole kinase

PDB Structure

PDB 5COJ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of ThiM from Vitamin B1 biosynthetic pathway of Staphylococcus aureus - Insights into a novel pro-drug approach addressing MRSA infections.
Drebes, J., Kunz, M., Windshugel, B., Kikhney, A.G., Muller, I.B., Eberle, R.J., Oberthur, D., Cang, H., Svergun, D.I., Perbandt, M., Betzel, C., Wrenger, C.
Sci Rep