CATH Classification

Domain Context

CATH Clusters

Superfamily Microbial ribonucleases
Functional Family Guanyl-specific ribonuclease T1

Enzyme Information

3.1.27.3
Ribonuclease T(1).
based on mapping to UniProt P00651
Two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in G-P with 2',3'-cyclic phosphate intermediates.
-!- Formerly EC 2.7.7.26 and EC 3.1.4.8.

UniProtKB Entries (1)

P00651
RNT1_ASPOR
Aspergillus oryzae RIB40
Guanyl-specific ribonuclease T1

PDB Structure

PDB 5BIR
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Dissecting histidine interactions of ribonuclease T1 with asparagine and glutamine replacements: analysis of double mutant cycles at one position.
De Vos, S., Doumen, J., Langhorst, U., Steyaert, J.
J.Mol.Biol.