CATH Classification

Domain Context

CATH Clusters

Superfamily 3.10.330.10
Functional Family Cell division cycle CDC48

Enzyme Information

3.6.4.6
Vesicle-fusing ATPase.
based on mapping to UniProt P55072
ATP + H(2)O = ADP + phosphate.
-!- A large family of ATP-hydrolyzing enzymes involved in the heterotypic fusion of membrane vesicles with target membranes and the homotypic fusion of various membrane compartments. -!- They belong to the AAA-type (ATPase associated with a variety of cell activities) ATPase superfamily. -!- They include peroxin, which apparently is involved in Zellweger's syndrome.

UniProtKB Entries (1)

P55072
TERA_HUMAN
Homo sapiens
Transitional endoplasmic reticulum ATPase

PDB Structure

PDB 5B6C
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Details of Ufd1 Binding to p97 and Their Functional Implications in ER-Associated Degradation
Le, L.T.M., Kang, W., Kim, J.Y., Le, O.T.T., Lee, S.Y., Yang, J.K.
PLoS ONE