CATH Classification

Domain Context

CATH Clusters

Superfamily Transferase(Phosphotransferase) domain 1
Functional Family Casein kinase II subunit alpha

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P68400
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P68400
CSK21_HUMAN
Homo sapiens
Casein kinase II subunit alpha

PDB Structure

PDB 5B0X
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure-activity relationship study of 4-(thiazol-5-yl)benzoic acid derivatives as potent protein kinase CK2 inhibitors
Ohno, H., Minamiguchi, D., Nakamura, S., Shu, K., Okazaki, S., Honda, M., Misu, R., Moriwaki, H., Nakanishi, S., Oishi, S., Kinoshita, T., Nakanishi, I., Fujii, N.
Bioorg.Med.Chem.