CATH Classification

Domain Context

CATH Clusters

Superfamily Farnesyl Diphosphate Synthase
Functional Family Geranylgeranyl diphosphate synthase

Enzyme Information

2.5.1.10
(2E,6E)-farnesyl diphosphate synthase.
based on mapping to UniProt Q08291
Geranyl diphosphate + isopentenyl diphosphate = diphosphate + (2E,6E)- farnesyl diphosphate.
-!- Some forms of this enzyme will also use dimethylallyl diphosphate as a substrate. -!- The enzyme will not accept larger prenyl diphosphates as efficient donors.

UniProtKB Entries (1)

Q08291
ISPA_GEOSE
Geobacillus stearothermophilus
Farnesyl diphosphate synthase

PDB Structure

PDB 5AYP
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of Bacillus stearothermophilus Farnesyl pyrophosphate synthase
Makabe, K., Kijima, T.
To Be Published