CATH Classification

Domain Context

CATH Clusters

Superfamily q2cbj1_9rhob like domain
Functional Family Verruculogen synthase

Enzyme Information

1.14.11.38
Verruculogen synthase.
based on mapping to UniProt Q4WAW9
Fumitremorgin B + 2-oxoglutarate + 2 O(2) + AH(2) = verruculogen + succinate + CO(2) + H(2)O + A.
-!- Found in the fungus Aspergillus fumigatus. -!- Both atoms of a dioxygen molecule are incorporated into verruculogen. -!- Involved in the biosynthetic pathways of several indole alkaloids such as fumitremorgin A.

UniProtKB Entries (1)

Q4WAW9
FTMF_ASPFU
Aspergillus fumigatus Af293
Verruculogen synthase

PDB Structure

PDB 4ZON
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Endoperoxide formation by an alpha-ketoglutarate-dependent mononuclear non-haem iron enzyme.
Yan, W., Song, H., Song, F., Guo, Y., Wu, C.H., Sae Her, A., Pu, Y., Wang, S., Naowarojna, N., Weitz, A., Hendrich, M.P., Costello, C.E., Zhang, L., Liu, P., Jessie Zhang, Y.
Nature