CATH Classification

Domain Context

CATH Clusters

Superfamily 3.60.21.10
Functional Family Serine/threonine-protein phosphatase

Enzyme Information

3.1.3.16
Protein-serine/threonine phosphatase.
based on mapping to UniProt P63087
[a protein]-serine/threonine phosphate + H(2)O = [a protein]- serine/threonine + phosphate.
-!- A group of enzymes removing the serine- or threonine-bound phosphate group from a wide range of phosphoproteins, including a number of enzymes which have been phosphorylated under the action of a kinase (cf. EC 3.1.3.48). -!- The spleen enzyme also acts on phenolic phosphates and phosphamides (cf. EC 3.9.1.1).

UniProtKB Entries (1)

P63087
PP1G_MOUSE
Mus musculus
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

PDB Structure

PDB 4V0V
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
G-actin provides substrate-specificity to eukaryotic initiation factor 2 alpha holophosphatases.
Chen, R., Rato, C., Yan, Y., Crespillo-Casado, A., Clarke, H.J., Harding, H.P., Marciniak, S.J., Read, R.J., Ron, D.
Elife