CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.58 | Methane Monooxygenase Hydroxylase; Chain G, domain 1 |
|
1.20.58.1880 |
Domain Context
CATH Clusters
| Superfamily | 1.20.58.1880 |
| Functional Family | REST corepressor 1 |
Enzyme Information
UniProtKB Entries (1)
| O60341 |
KDM1A_HUMAN
Homo sapiens
Lysine-specific histone demethylase 1A
|
PDB Structure
| PDB | 4UVB |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Synthesis, Biological Activity and Mechanistic Insights of 1-Substituted Cyclopropylamine Derivatives: A Novel Class of Irreversible Inhibitors of Histone Demethylase Kdm1A.
Eur.J.Med.Chem.
|