CATH Classification

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family Monoglyceride lipase

Enzyme Information

3.1.1.23
Acylglycerol lipase.
based on mapping to UniProt Q99685
Hydrolyzes glycerol monoesters of long-chain fatty acids.

UniProtKB Entries (1)

Q99685
MGLL_HUMAN
Homo sapiens
Monoglyceride lipase

PDB Structure

PDB 4UUQ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Selective Blockade of the Hydrolysis of the Endocannabinoid 2-Arachidonoylglycerol Impairs Learning and Memory Performance While Producing Antinociceptive Activity in Rodents.
Griebel, G., Pichat, P., Beeske, S., Leroy, T., Redon, N., Jacquet, A., Francon, D., Bert, L., Even, L., Lopez-Grancha, M., Tolstykh, T., Sun, F., Yu, Q., Brittain, S., Arlt, H., He, T., Zhang, B., Wiederschain, D., Bertrand, T., Houtmann, J., Rak, A., Vallee, F., Michot, N., Auge, F., Menet, V., Bergis, O.E., George, P., Avenet, P., Mikol, V., Didier, M., Escoubet, J.
Sci.Rep.