CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleotide cyclase
Functional Family Adenylate cyclase type 10

Enzyme Information

4.6.1.1
Adenylate cyclase.
based on mapping to UniProt Q96PN6
ATP = 3',5'-cyclic AMP + diphosphate.
-!- Also acts on dATP to form 3',5'-cyclic dAMP. -!- Requires pyruvate. -!- Activated by NAD(+) in presence of EC 2.4.2.31.

UniProtKB Entries (1)

Q96PN6
ADCYA_HUMAN
Homo sapiens
Adenylate cyclase type 10

PDB Structure

PDB 4USV
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Analysis of Human Soluble Adenylyl Cyclase and Crystal Structures of its Nucleotide Complexes -Implications for Cyclase Catalysis and Evolution.
Kleinbolting, S., Van Den Heuvel, J., Steegborn, C.
FEBS J.