1 keywords

CATH Domain 4s10A00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.40 Immunoglobulin-like
Homologous Superfamily 2.60.40.10 Immunoglobulins

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family

Enzyme Information

UniProtKB Entries (1)

P06396
GELS_HUMAN
Homo sapiens
Gelsolin

PDB Structure

PDB 4S10
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
An ER-directed gelsolin nanobody targets the first step in amyloid formation in a gelsolin amyloidosis mouse model.
Van Overbeke, W., Wongsantichon, J., Everaert, I., Verhelle, A., Zwaenepoel, O., Loonchanta, A., Burtnick, L.D., De Ganck, A., Hochepied, T., Haigh, J., Cuvelier, C., Derave, W., Robinson, R.C., Gettemans, J.
Hum.Mol.Genet.