CATH Classification

Domain Context

CATH Clusters

Superfamily Glutamine synthetase, N-terminal domain
Functional Family Glutamine synthetase

Enzyme Information

6.3.1.2
Glutamine synthetase.
based on mapping to UniProt P12425
ATP + L-glutamate + NH(3) = ADP + phosphate + L-glutamine.
-!- Glutamine synthetase, which catalyzes the incorporation of ammonium into glutamate, is a key enzyme of nitrogen metabolism found in all domains of life. -!- Several types have been described, differing in their oligomeric structures and cofactor requirements.

UniProtKB Entries (1)

P12425
GLN1A_BACSU
Bacillus subtilis subsp. subtilis str. 168
Glutamine synthetase

PDB Structure

PDB 4S0R
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structures of regulatory machinery reveal novel molecular mechanisms controlling B. subtilis nitrogen homeostasis.
Schumacher, M.A., Chinnam, N.B., Cuthbert, B., Tonthat, N.K., Whitfill, T.
Genes Dev.