CATH Classification

Domain Context

CATH Clusters

Superfamily 1.20.1260.10
Functional Family Aldehyde decarbonylase

Enzyme Information

4.1.99.5
Aldehyde oxygenase (deformylating).
based on mapping to UniProt Q54764
A long-chain aldehyde + O(2) + 2 NADPH = an alkane + formate + H(2)O + 2 NADP(+).
-!- Involved in the biosynthesis of alkanes. -!- The enzyme from the cyanobacterium Nostoc punctiforme PCC 73102 is only active in vitro in the presence of ferredoxin, ferredoxin reductase and NADPH, and produces mostly C(15) to C(17) alkanes. -!- The enzyme from pea (Pisum sativum) produces alkanes of chain length C18 to C32 and is inhibited by metal-chelating agents. -!- The substrate for this enzyme is formed by EC 1.2.1.80.

UniProtKB Entries (1)

Q54764
ALDEC_SYNE7
Synechococcus elongatus PCC 7942
Aldehyde decarbonylase

PDB Structure

PDB 4RC8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural insights into the catalytic mechanism of aldehyde-deformylating oxygenases
Jia, C., Li, M., Li, J., Zhang, J., Zhang, H., Cao, P., Pan, X., Lu, X., Chang, W.
Protein Cell