CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphatase 2C, C-terminal domain suprefamily
Functional Family Protein phosphatase, Mg2+/Mn2+ dependent 1A

Enzyme Information

3.1.3.16
Protein-serine/threonine phosphatase.
based on mapping to UniProt P35813
[a protein]-serine/threonine phosphate + H(2)O = [a protein]- serine/threonine + phosphate.
-!- A group of enzymes removing the serine- or threonine-bound phosphate group from a wide range of phosphoproteins, including a number of enzymes which have been phosphorylated under the action of a kinase (cf. EC 3.1.3.48). -!- The spleen enzyme also acts on phenolic phosphates and phosphamides (cf. EC 3.9.1.1).

UniProtKB Entries (1)

P35813
PPM1A_HUMAN
Homo sapiens
Protein phosphatase 1A

PDB Structure

PDB 4RAG
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The catalytic role of the M2 metal ion in PP2C alpha
Pan, C., Tang, J.Y., Xu, Y.F., Xiao, P., Liu, H.D., Wang, H.A., Wang, W.B., Meng, F.G., Yu, X., Sun, J.P.
Sci Rep